Endocrine Abstracts

Osteoporosis in men is recently recognized as a major underestimated public health problem. In 2050, the incidence of hip fracture in men is expected to increase by 310% worldwide. After the age of 50, one out of three osteoporotic fractures are seen in men. Men suffering any major fracture have a higher mortality rate than women osteoporotic fractures. Screening is usually recommended in many guidelines above the age of 65 or 70 years and those younger aged with risk for oste...

PurposeObesity, diabetes mellitus, and metabolic syndrome (MetS) have been known to be associated with increased skin autofluorescence (SAF). In patients with MetS, higher SAF measurements were found to be associated with an increased number of the components of MetS. In this cross-sectional study, we aimed to evaluate the association of MetS and its’ components with skin autofluorescence in severely obese patients and to examine whether diabetes or...

Bariatric surgery patients are at risk of decreasing in muscle mass, vitamin and protein deficiency. The aim of this study is to asses muscle strength, serum protein and vitamin levels after bariatric surgery.Methods: 264 patients underwent bariatric surgery who completed 6 th month policlinic visits were included in the study. Patients were followed appropriately supplemented protein and vitamins as suggested; all study parameters were assessed before a...

Although bariatric surgery has beneficial effects on obesity related complications, rapid weight loss might have negative effects on skeletal health. The objective of our study was to evaluate changes in bone mineral density (BMD) and bone biochemical markers in patients, before and 1 year after bariatric surgery.Methods: One hundred and two morbidly obese subjects (mean 43±15 years, BMI 48,5 g/cm2) performed either Roux en Y gastric bypa...

Levels of thyroid hormones may effect the levels of the glycation product and those of the oxidation products.Objective: To evaluate the relationship between skin autofluorescence (SAF), and serum advanced glycation end products (AGEs) parameters in hypothyroid and hyperthyroid patients.Method: Newlydiagnosed or untreated 100 overt and subclinical hypothyroid patients (42±13 yrs) and 50 overt-subclinical hyperthyroid patients ...

Introduction: Although medullary thyroid cancer (MTC) constitutes 2–4% of all thyroid cancers, it is associated with higher mortality compared to differentiated thyroid carcinomas. Here we present long term clinical results of medullary carcinoma patients’ follow-up in our center.Methods and results: MTC was detected in 27 (3.73%) patients of 850 thyroid cancer cases who were followed-up between 2004 and 2020 at the Marmara University School ...

A 76-year-old female patient has been admitted to various hospitals with complaints of low blood sugar especially in the morning, sweating, fainting, loss of consciousness, have been suspected of insulinoma with the results of the latest examinations made in 2012, but no focus has been detected. With the same complaints, the patient who applied to our out-patient clinic in December 2017 was subjected to an extended hunger test and invested for further research. Previously, the...

Introduction:Acromegaly is caused by excess levels of growth hormone (GH) and insulin-like growth factor 1 (IGF1), which usually result from a pituitary adenoma. At the presence of classical symptoms, the diagnosis is confirmed by increased serum IGF1 concentrations and high serum levels of GH that are not suppressed in an an oral glucose tolerance test (OGTT). A nadir GH cut-off of 0.4 µg/lwith ultrasensitive assays is considered as diagnostic. How...

Objective: Neurofibromatosis type 1 is an autosomal dominant inherited neurocutaneous condition characterized with multipl cafe-au-lait spots, neurofibromas, predisposition to malignancies, and the incidence of disease is 1:3000. Patients are diagnosed according to diagnostic criteria and 97% of the patents meet the criteria before 8 years of old. Diagnosis and follow-up of patients for manifestations of neurofibromatosis is important for early diagnosis and treatment of malig...

Objective: Severe hypertriglyceridemia is one of the leading causes of acute pancreatitis which is associated with increased mortality and morbidity. Here we evaluate the effectiveness of plasmapheresis on triglyceride levels in our group of patients who had plasmapheresis in our endocrinology clinic.Method: We retrospectively evaluate clinical and laboratory reports between 2016–2018, for demographic parameters and the lipid levels before and immed...